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KMID : 1144820190250030288
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대한의생명과학회지
2019 Volume.25 No. 3 p.288 ~ p.292
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Antimicrobial Activities of Extracts of Camellia sinensis (L.) O. Kuntze and Profile of Antimicrobial Agents Resistance for Carbapenem-Resistant Enterobacteriaceae
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Yum Jong-Hwa
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Abstract
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In vitro antimicrobial activities of hot water extracts of Camellia sinensis (L.) O. Kuntze, for carbapenem-resistant Enterobacteriaceae (CRE) were compared to commonly used conventional antimicrobial agents. CRE was not only resistant to imipenem, meropenem or ertapenem, but also to various antimicrobial agents, such as amikacin (> 128 μg/mL). The hot water extracts of Camellia sinensis (L.) O. Kuntze had the lowest MIC (0.06~0.5 μL/mL) of the carbapenem-resistant E. coli, K. pneumoniae, and Enterobacter spp. tested, and it was possible more potent than various conventional antimicrobial agents. Synergistic combinations of the extract with used commonly antimicrobial agents might even improve its antimicrobial chemotherapy property.
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KEYWORD
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Camellia sinensis (L.) O. Kuntze, Enterobacteriaceae, Carbepenem resistant, Catechin, Antimicrobial agent
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